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1

Novel Synthesis of 3,4-Diarylisoxazole Analogues of Valdecoxib: Reversal Cyclooxygenase-2 Selectivity by Sulfonamide Group Removal

Di Nunno, Leonardo, Vitale, Paola, Scilimati, Antonio, Tacconelli, Stefania, Patrignani, Paola

Journal:

Journal of Medicinal Chemistry

Année:

2004

Langue:

english

Fichier:

PDF, 158 KB

english, 2004

2

Mechanistic and Pharmacological Issues of Aspirin as an Anticancer Agent

Dovizio, Melania, Tacconelli, Stefania, Sostres, Carlos, Ricciotti, Emanuela, Patrignani, Paola

Journal:

Pharmaceuticals

Année:

2012

Langue:

english

Fichier:

PDF, 446 KB

english, 2012

3

Clinical pharmacology of etoricoxib: a novel selectiveCOX2 inhibitor

Patrignani, Paola, Capone, Marta L, Tacconelli, Stefania

Journal:

Expert Opinion on Pharmacotherapy

Année:

2003

Langue:

english

Fichier:

PDF, 710 KB

english, 2003

4

Differential association between human prostacyclin receptor polymorphisms and the development of venous thrombosis and intimal hyperplasia: a clinical biomarker study

Patrignani, Paola, Di Febbo, Concetta, Tacconelli, Stefania, Douville, Karen, Guglielmi, Maria D., Horvath, Ryan J., Ding, Min, Sierra, Kent, Stitham, Jeremiah, Gleim, Scott, Baccante, Giovanna, Moret

Journal:

Pharmacogenetics and Genomics

Année:

2008

Langue:

english

Fichier:

PDF, 160 KB

english, 2008

5

Nonsteroidal anti-inflammatory drugs and cardiovascular safety – translating pharmacological data into clinical readouts

Tacconelli, Stefania, Bruno, Annalisa, Grande, Rosalia, Ballerini, Patrizia, Patrignani, Paola

Journal:

Expert Opinion on Drug Safety

Année:

2017

Langue:

english

Fichier:

PDF, 1.11 MB

english, 2017

6

Increased matrix metalloproteinase-9 secretion in short-term tissue cultures of prostatic tumor cells

Claudio Festuccia, Mauro Bologna, Carlo Vicentini, Antonella Tacconelli, Roberto Miano, Stefania Violini, Andrew R. Mackay

Journal:

International Journal of Cancer

Année:

1996

Langue:

english

Fichier:

PDF, 1.03 MB

english, 1996

7

Variability among nonsteroidal antiinflammatory drugs in risk of upper gastrointestinal bleeding

Elvira L. Massó González, Paola Patrignani, Stefania Tacconelli, Luis A. García Rodríguez

Journal:

Arthritis & Rheumatism

Année:

2010

Langue:

english

Fichier:

PDF, 96 KB

english, 2010

8

Low-dose naproxen interferes with the antiplatelet effects of aspirin in healthy subjects: Recommendations to minimize the functional consequences

Paola Anzellotti, Marta L. Capone, Anita Jeyam, Stefania Tacconelli, Annalisa Bruno, Paola Tontodonati, Luigia Di Francesco, Linda Grossi, Giulia Renda, Gabriele Merciaro, Patrizia Di Gregorio, Thomas

Journal:

Arthritis & Rheumatism

Année:

2011

Langue:

english

Fichier:

PDF, 284 KB

english, 2011

9

Effects of acetaminophen on constitutive and inducible prostanoid biosynthesis in human blood cells

Maria G Sciulli, Francesca Seta, Stefania Tacconelli, Marta L Capone, Emanuela Ricciotti, Giuseppa Pistritto, Paola Patrignani

Journal:

British Journal of Pharmacology

Année:

2003

Langue:

english

Fichier:

PDF, 210 KB

english, 2003

10

Pharmacodynamic of cyclooxygenase inhibitors in humans

Marta L. Capone, Stefania Tacconelli, Luigia Di Francesco, Andrea Sacchetti, Maria G. Sciulli, Paola Patrignani

Journal:

Prostaglandins and Other Lipid Mediators

Année:

2007

Langue:

english

Fichier:

PDF, 304 KB

english, 2007

11

New insights into COX-2 biology and inhibition

Paola Patrignani, Stefania Tacconelli, Maria Gina Sciulli, Marta L. Capone

Journal:

Brain Research Reviews

Année:

2005

Langue:

english

Fichier:

PDF, 332 KB

english, 2005

12

Mechanisms of the antitumoural effects of aspirin in the gastrointestinal tract

Annalisa Bruno, Melania Dovizio, Stefania Tacconelli, Paola Patrignani

Journal:

Best Practice & Research Clinical Gastroenterology

Année:

2012

Langue:

english

Fichier:

PDF, 553 KB

english, 2012

13

Pharmacodynamic interaction of naproxen with low-dose aspirin in healthy subjects

Marta L. Capone, Maria G. Sciulli, Stefania Tacconelli, Marilena Grana, Emanuela Ricciotti, Giulia Renda, Patrizia Di Gregorio, Gabriele Merciaro, Paola Patrignani

Journal:

Journal of the American College of Cardiology

Année:

2005

Langue:

english

Fichier:

PDF, 200 KB

english, 2005

14

Role of Dose Potency in the Prediction of Risk of Myocardial Infarction Associated With Nonsteroidal Anti-Inflammatory Drugs in the General Population

Luis Alberto García Rodríguez, Stefania Tacconelli, Paola Patrignani

Journal:

Journal of the American College of Cardiology

Année:

2008

Langue:

english

Fichier:

PDF, 699 KB

english, 2008

15

Enhaced cortisol secretion does not control aspirin-insensitivess thromboxane biosynthesis in patients with acute coronary syndromes

Giulia Renda, Maria G. Sciulli, Francesca Seta, Stefania Tacconelli, Marta L. Capone, Antonio Rebuzzi, Paola Patrignani

Journal:

Journal of the American College of Cardiology

Année:

2002

Langue:

english

Fichier:

PDF, 118 KB

english, 2002

16

Synthesis, Pharmacological Characterization, and Docking Analysis of a Novel Family of Diarylisoxazoles as Highly Selective Cyclooxygenase-1 (COX-1) Inhibitors

Vitale, Paola, Tacconelli, Stefania, Perrone, Maria Grazia, Malerba, Paola, Simone, Laura, Scilimati, Antonio, Lavecchia, Antonio, Dovizio, Melania, Marcantoni, Emanuela, Bruno, Annalisa, Patrignani,

Journal:

Journal of Medicinal Chemistry

Année:

2013

Langue:

english

Fichier:

PDF, 2.00 MB

english, 2013

17

Effects of estrogen on endothelial prostanoid production and cyclooxygenase-2 and heme oxygenase-1 expression

Marcantoni, Emanuela, Di Francesco, Luigia, Totani, Licia, Piccoli, Antonio, Evangelista, Virgilio, Tacconelli, Stefania, Patrignani, Paola

Journal:

Année:

2012

Langue:

english

Fichier:

PDF, 830 KB

english, 2012

18

Sa1962 Determinants of Eicosanoid Generation and Inhibition in Human Gastric Mucosa In Vitro

Sostres, Carlos, Tacconelli, Stefania, Bruno, Annalisa, Francesco, Luigia Di, Arruebo, Maria, Jimenez, Pilar, Patrignani, Paola, Lanas, Angel

Journal:

Gastroenterology

Année:

2013

Langue:

english

Fichier:

PDF, 182 KB

english, 2013

19

NSAIDs and cardiovascular disease: transducing human pharmacology results into clinical read-outs in the general population

Capone, Marta L., Tacconelli, Stefania, Garcia Rodriguez, Luis, Patrignani, Paola

Journal:

Pharmacological Reports

Année:

2010

Langue:

english

Fichier:

PDF, 103 KB

english, 2010

20

W1003 Variability of Risk of Upper Gastrointestinal Bleeding Among Nonsteroidal Anti-Inflammatory Drugs

Masso-Gonzalez, Elvira L., Patrignani, Paola, Tacconelli, Stefania, Rodriguez, Luis A. Garcia

Journal:

Gastroenterology

Année:

2010

Langue:

english

Fichier:

PDF, 161 KB

english, 2010

21

Isoprostanes and other markers of peroxidation in atherosclerosis

Patrignani, Paola, Tacconelli, Stefania

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 81 KB

english, 2005

22

Cardiovascular effects of valdecoxib: transducing human pharmacology results into clinical read-outs

Capone, Marta L, Tacconelli, Stefania, Francesco, Luigia Di, Petrelli, Maria, Patrignani, Paola

Journal:

Expert Opinion on Drug Safety

Année:

2008

Langue:

english

Fichier:

PDF, 276 KB

english, 2008

23

Clinical pharmacology of etoricoxib

Capone, Marta L, Tacconelli, Stefania, Patrignani, Paola

Journal:

Expert Opinion on Drug Metabolism & Toxicology

Année:

2005

Langue:

english

Fichier:

PDF, 342 KB

english, 2005

24

Variability in the Response to Non-Steroidal Anti-Inflammatory Drugs: Mechanisms and Perspectives

Bruno, Annalisa, Tacconelli, Stefania, Patrignani, Paola

Journal:

Basic & Clinical Pharmacology & Toxicology

Année:

2014

Langue:

english

Fichier:

PDF, 157 KB

english, 2014

25

Managing the adverse effects of nonsteroidal anti-inflammatory drugs

Patrignani, Paola, Tacconelli, Stefania, Bruno, Annalisa, Sostres, Carlos, Lanas, Angel

Journal:

Expert Review of Clinical Pharmacology

Année:

2011

Langue:

english

Fichier:

PDF, 2.84 MB

english, 2011

26

The Biochemical Selectivity of Novel COX-2 Inhibitors in Whole Blood Assays of COX-isozyme Activity

Tacconelli, Stefania, Capone, Marta L., Sciulli, Maria G., Ricciotti, Emanuela, Patrignani, Paola

Journal:

Current Medical Research and Opinion

Année:

2002

Langue:

english

Fichier:

PDF, 331 KB

english, 2002

27

Gut Microbiota, Host Gene Expression, and Aging

Patrignani, Paola, Tacconelli, Stefania, Bruno, Annalisa

Journal:

Journal of Clinical Gastroenterology

Année:

2014

Langue:

english

Fichier:

PDF, 155 KB

english, 2014

28

Glycopeptide Resistance among Coagulase‐Negative Staphylococci that Cause Bacteremia: Epidemiological and Clinical Findings from a Case‐Control Study

Tacconelli, Evelina, Tumbarello, Mario, Donati, Katleen de Gaetano, Bettio, Manola, Spanu, Teresa, Leone, Fiammetta, Sechi, Leonardo A., Zanetti, Stefania, Fadda, Giovanni, Cauda, Roberto

Journal:

Clinical Infectious Diseases

Année:

2001

Langue:

english

Fichier:

PDF, 165 KB

english, 2001

29

Inside epoxyeicosatrienoic acids and cardiovascular disease

Tacconelli, Stefania, Patrignani, Paola

Journal:

Frontiers in Pharmacology

Année:

2014

Langue:

english

Fichier:

PDF, 685 KB

english, 2014

30

Dysregulated post-transcriptional control of COX-2 gene expression in gestational diabetic endothelial cells

Di Francesco, Luigia, Dovizio, Melania, Trenti, Annalisa, Marcantoni, Emanuela, Moore, Ashleigh, O'Gaora, Peadar, McCarthy, Cathal, Tacconelli, Stefania, Bruno, Annalisa, Alberti, Sara, Gizzo, Salvato

Journal:

British Journal of Pharmacology

Année:

2015

Fichier:

PDF, 1.30 MB

2015

31

Dysregulated post-transcriptional control of COX-2 gene expression in gestational diabetic endothelial cells

Di Francesco, Luigia, Dovizio, Melania, Trenti, Annalisa, Marcantoni, Emanuela, Moore, Ashleigh, O'Gaora, Peadar, McCarthy, Cathal, Tacconelli, Stefania, Bruno, Annalisa, Alberti, Sara, Gizzo, Salvato

Journal:

British Journal of Pharmacology

Année:

2015

Langue:

english

Fichier:

PDF, 1.30 MB

english, 2015

32

Azole Susceptibility Patterns and Genetic Relationship Among Oral Candida Strains Isolated in the Era of Highly Active Antiretroviral Therapy

Tacconelli, Evelina, Bertagnolio, Silvia, Posteraro, Brunella, Tumbarello, Mario, Boccia, Stefania, Fadda, Giovanni, Cauda, Roberto

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Année:

2002

Fichier:

PDF, 523 KB

2002

33

1068 Direct Evidence for Long-Lasting Acetylation of Cyclooxygenase-1 Associated With Reduction of Colorectal Mucosa Prostaglandin E2 Levels and Ribosomal Protein S6 Phosphorylation by Low-Dose Aspirin in Subjects Undergoing Colorectal Cancer Screening

Patrignani, Paola, Sacco, Angela, Sostres, Carlos, Bruno, Annalisa, Dovizio, Melania, Piazuelo, Elena, Di Francesco, Luigia, Schiavone, Simone, Tacconelli, Stefania, Ferrandez, Angel, Patrono, Carlo,

Journal:

Gastroenterology

Année:

2016

Langue:

english

Fichier:

PDF, 121 KB

english, 2016

34

Reduced variability to aspirin antiplatelet effect by the coadministration of statins in high-risk patients for cardiovascular disease

Tacconelli, Stefania, Dovizio, Melania, Di Francesco, Luigia, Meneguzzi, Alessandra, D'Agostino, Ilaria, Evangelista, Virgilio, Manarini, Stefano, Capone, Marta L., Grossi, Linda, Porreca, Ettore, Di

Journal:

Clinical Pharmacology & Therapeutics

Année:

2018

Langue:

english

Fichier:

PDF, 908 KB

english, 2018

35

P2Y12 Receptors in Tumorigenesis and Metastasis

Ballerini, Patrizia, Dovizio, Melania, Bruno, Annalisa, Tacconelli, Stefania, Patrignani, Paola

Journal:

Frontiers in Pharmacology

Année:

2018

Langue:

english

Fichier:

PDF, 1.29 MB

english, 2018

36

Antithrombotic Agents and Cancer

Bruno, Annalisa, Dovizio, Melania, Tacconelli, Stefania, Contursi, Annalisa, Ballerini, Patrizia, Patrignani, Paola

Journal:

Année:

2018

Langue:

english

Fichier:

PDF, 906 KB

english, 2018

37

miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction

Saul, Meike J., Baumann, Isabell, Bruno, Annalisa, Emmerich, Anne C., Wellstein, Julia, Ottinger, Sarah M., Contursi, Annalisa, Dovizio, Melania, Donnini, Sandra, Tacconelli, Stefania, Raouf, Joan, Id

Journal:

The FASEB Journal

Année:

2019

Fichier:

PDF, 1.67 MB

2019

38

miR-574-5p as RNA decoy for CUGBP1 stimulates human lung tumor growth by mPGES-1 induction

Saul, Meike J., Baumann, Isabell, Bruno, Annalisa, Emmerich, Anne C., Wellstein, Julia, Ottinger, Sarah M., Contursi, Annalisa, Dovizio, Melania, Donnini, Sandra, Tacconelli, Stefania, Raouf, Joan, Id

Journal:

The FASEB Journal

Année:

2019

Langue:

english

Fichier:

PDF, 1.67 MB

english, 2019

39

Platelet-specific deletion of cyclooxygenase-1 ameliorates dextran sulfate sodium-induced colitis in mice

Sacco, Angela, Bruno, Annalisa, Contursi, Annalisa, Dovizio, Melania, Tacconelli, Stefania, Ricciotti, Emanuela, Guillem-Llobat, Paloma, Salvatore, Tania, Di Francesco, Luigia, Fullone, Rosa, Ballerin

Journal:

Journal of Pharmacology and Experimental Therapeutics

Année:

2019

Langue:

english

Fichier:

PDF, 729 KB

english, 2019

40

Pharmacological Characterization of the Microsomal Prostaglandin E2 Synthase-1 Inhibitor AF3485 In Vitro and In Vivo

Di Francesco, Luigia, Bruno, Annalisa, Ricciotti, Emanuela, Tacconelli, Stefania, Dovizio, Melania, Guillem-Llobat, Paloma, Alisi, Maria Alessandra, Garrone, Beatrice, Coletta, Isabella, Mangano, Gior

Journal:

Frontiers in Pharmacology

Année:

2020

Fichier:

PDF, 2.01 MB

2020

41

Characterization of cyclooxygenase-2 acetylation and prostanoid inhibition by aspirin in cellular systems

Tacconelli, Stefania, Contursi, Annalisa, Falcone, Lorenza, Mucci, Matteo, D'Agostino, Ilaria, Fullone, Rosa, Sacco, Angela, Zucchelli, Mirco, Bruno, Annalisa, Ballerini, Patrizia, Dovizio, Melania, P

Journal:

Biochemical Pharmacology

Année:

2020

Fichier:

PDF, 1.99 MB

2020

42

Pharmacological characterization of the biosynthesis of prostanoids and hydroxyeicosatetraenoic acids in human whole blood and platelets by targeted chiral lipidomics analysis

Tacconelli, Stefania, Fullone, Rosa, Dovizio, Melania, Pizzicoli, Graziana, Marschler, Stephanie, Bruno, Annalisa, Zucchelli, Mirco, Contursi, Annalisa, Ballerini, Patrizia, Patrignani, Paola

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Année:

2020

Fichier:

PDF, 674 KB

2020

43

Multifaceted Functions of Platelets in Cancer: From Tumorigenesis to Liquid Biopsy Tool and Drug Delivery System

Dovizio, Melania, Ballerini, Patrizia, Fullone, Rosa, Tacconelli, Stefania, Contursi, Annalisa, Patrignani, Paola

Journal:

International Journal of Molecular Sciences

Année:

2020

Fichier:

PDF, 1.03 MB

2020